Pieter Oliehoek wrote a thesis on this subject in a joint project of the Centre for Genetic Resources the Netherlands and the Animal Breeding and Genomics Centre of Wageningen University. The thesis shows that the studied captive populations lost most of the genetic variation that was present in the founders. It also shows that populations could still double their genetic diversity with a adequate mating plan with optimal contributions. E.g the base population of the Icelandic Sheepdog consisted of 36 founders and the current diversity is equal to only 2.2 equally contributing founders with no loss of founder alleles in descendants. In the thesis a methods for correction of missing parents in pedigrees are studied and effects of errors in pedigrees are calculated.
maandag 20 april 2009
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